Wegovy (Semaglutide): The solution for weight loss – how it works, how much you lose, side effects and dosages

Wigwam It is a relatively new drug on the obesity treatment market. Many people are looking for effective solutions for weight loss, and for some, the drugs are essential help. At the very beginning, it is worth getting to know the name and its importance. This is a drug that contains the active ingredient Semaglutide, which is also known by other trade names, such as Ozempic.
Although both are based on the same molecule, Vigabatrin was developed specifically for patients who are obese or significantly overweight. In the following guide, we will explain how Vigabatrin works, who it is intended for, what are the available doses, what side effects may occur, and more. We will also detail the differences between it and similar drugs such as Ozempic and Mounjaro.

What is Wegovy?

Wegovy It is an innovative drug specifically developed to aid weight loss in people who are obese or significantly overweight. It contains the active ingredient semaglutide, which is considered a GLP-1 receptor agonist (Glucagon-Like Peptide-1 Receptor Agonist).
This substance increases the feeling of satiety and reduces appetite. In this way, those who use it feel fuller for longer. In addition, gastric emptying slows down. This increases the chance of reducing daily calorie intake. The drug Vigobes is currently approved as a treatment for obesity, subject to specific medical conditions.

Semaglutide

Semaglutide is the active ingredient responsible for the mechanism that makes GLP-1 drugs unique. It mimics a natural hormone that helps the body control appetite and the feeling of fullness. Doctors began to include semaglutide in patients with type 2 diabetes, as it also improves glycemic balance. However, when researchers noticed a relatively large effect on weight loss, it was decided to develop a specific preparation for obesity – and thus Vigoby was born.

Vigabatrin vs Ozempic

While Vigo and Ozempic both contain semaglutide, there are important differences. Ozempic is primarily used to treat type 2 diabetes, with one of its secondary benefits being weight loss. Vigo, on the other hand, is primarily intended to treat obesity or overweight with risk factors.
The difference is also reflected in the dosage levels: Ozempic is given in different doses (for example, up to 1 mg per week), while Vigobes reaches up to 2.4 mg per week. Thus, the maximum dose of Vigobes is higher and is specifically aimed at weight loss.

Who is Vigobi for?

Vigobi is suitable for adults with a BMI of 30 or higher, who are defined as obese, or for adults with a BMI of 27 or higher (overweight) when accompanied by a significant medical risk factor. Possible factors are type 2 diabetes, hypertension, dyslipidemia (abnormal levels of blood fats), and more.
Due to its effect of increasing satiety and reducing appetite, Vigobi is intended to be integrated as part of a comprehensive lifestyle change program. In other words, the treatment does not stand alone. It is highly recommended to combine it with an adapted diet and regular physical activity.

Obesity or overweight

Obesity is defined as a BMI (Body Mass Index) of 30 or higher. Overweight is defined as a BMI between 25 and 29.9. However, in the case of Vigobi, the indication for people with a BMI of 27 or higher only applies when there is at least one accompanying medical condition related to weight.
These medical conditions often include cardiac risk, impaired blood lipid profile, pre-diabetes, or type 2 diabetes itself. When Vigabatrin is combined with changes in eating habits and exercise, the likelihood of achieving significant weight loss increases.

Why is it important to incorporate a healthy lifestyle?

No medicine can completely replace the need to maintain a healthy lifestyle. Vigobi helps control hunger, but it works better when combined with a proper diet. Exercise also enhances the positive effect of the medicine. People who exercise regularly experience greater weight loss and an overall improvement in their quality of life.

How does Wegovy work?

Vigabatrin's mechanism of action is based on mimicking the hormone GLP-1. This hormone is naturally secreted in the digestive tract and is associated with the feeling of fullness. When its level increases, it helps reduce appetite, slow down the process of gastric emptying, and control blood sugar levels.

Increasing the feeling of satiety

Vigobi increases satiety by stimulating GLP-1 receptors in the brain. In practice, you feel fuller after eating smaller amounts of food. This results in a reduction in calorie intake, if you follow a healthy diet.

Reducing appetite and slowing gastric emptying

In addition to increasing satiety, Vigobi also reduces appetite and slows gastric emptying. This means that food stays in the digestive tract longer, so there is a feeling of fullness for a longer period of time. Combined with reducing the desire to eat between meals, it is easier to maintain a calorie deficit and lose weight.

Administration route: Subcutaneous injection

Vigabatrin is given by subcutaneous injection using a self-administered pen. The injection is usually given once a week, usually in the arm, thigh, or abdomen. The pen automatically adjusts the dose to the desired level, depending on the patient's stage (gradual dose escalation).

Dosages and instructions for taking Vigoby

One of the most common questions is about the exact dosage of Vigoby. Like many drugs in the GLP-1 receptor agonist class, there is a gradual increase in dosage to reduce gastrointestinal side effects and allow the body to adapt.

Wegovy 0.25 mg

This is the lowest starting dose. Many doctors recommend starting with Vigobi 0.25 mg once a week for the first four weeks. This period allows the body to get used to the effect on the digestive system.

Wegovy 0.5 mg

After about a month at the initial dose, you move to a higher dose: usually 0.5 mg once a week. This phase also lasts several weeks until you reach stability in terms of adaptation. The goal of the slow transition is to reduce nausea and digestive disorders.

Wegovy 1 mg

In the next stage, patients move to a dosage of 1 mg per week. Staying at this dosage usually lasts about four weeks, but the duration may vary depending on the medical condition and the instructions of the treating physician.

Wegovy 1.7 mg

In the next step, the dose increases to 1.7 mg per week. Here too, it is recommended to wait about a month before increasing again. At this stage, some patients already experience a more significant decrease in appetite and weight. However, continued monitoring is still necessary to assess tolerability.

Wegovy 2.4 mg

The maximum and therapeutic dose is 2.4 mg once a week. This is considered the designated dose to maintain maximum weight loss effect. After several weeks of treatment with 2.4 mg, a balance is created between maximum effectiveness and possible side effects.

Injection frequency and correct instructions

Vigabatrin is usually injected once a week, on the same day and at approximately the same time. It is a good idea to choose a different injection site each time (for example, once in the abdomen, once in the thigh). If you miss a dose, you can inject within five more days. After that, continue with your weekly cycle as usual.

How long does it take for Vigobi to take effect?

Many people want to know how long it will take to start seeing significant weight loss results when using VigRX Plus. It is important to remember that every person’s body is different, so the response may vary. Typically, people begin to experience a reduction in appetite and food cravings within the first few weeks.
However, weight loss is usually well-appreciated within 8–12 weeks of starting treatment. It should be remembered that the gradual increase in dose may slightly delay the strong effect. When a dose of 2.4 mg is reached and maintained regularly, a stable and continuous loss can be expected.

How long does Vigova stay in the body?

Semaglutide is a substance with a long half-life (about 7 days). This means that the substance remains in the body for a long time after a single injection. This is why a weekly dose is sufficient to maintain a stable level of the drug in the blood. About three to four weeks after stopping treatment, the substance is usually almost completely cleared from the body.

How much does it cost with Vigobi?

Clinical data shows that many people are able to achieve a 10%–15% weight loss within a few months of treatment with Vigovi, along with diet and exercise. There are also cases of greater weight loss, especially if a healthy lifestyle is consistently maintained.
However, one should not expect an immediate "miracle." Results are also related to the patient's personal commitment. Furthermore, factors such as age, gender, concomitant medical conditions, and level of physical activity also have an impact. It is important to set realistic goals and work closely with medical and nutritional counseling.

Side effects of Vigovaya

Like all medicines, Vigabatrin may cause side effects. These usually occur at the beginning of treatment or when the dose is increased, and then decrease over time.

Common side effects

• Nausea and vomitingNausea: Nausea is one of the most common complaints. In some cases, vomiting will also occur, especially when the dosage is increased.
• Diarrhea or constipation: Changes in bowel habits are a common occurrence with semaglutide treatment. Some people will experience mild diarrhea, others may experience constipation.
• Stomach pain: Some patients report general abdominal discomfort or mild pain. This is usually a temporary condition that gradually resolves.

Less common or serious side effects

• Inflammation of the pancreas (pancreatitis): There is a small risk of developing pancreatitis. Watch for symptoms such as severe pain in the upper abdomen.
• Gallstones: Rapid weight loss may increase the formation of gallstones, so it is important to continue monitoring and report any unusual pain in the upper right side of the abdomen to your doctor.
• Thyroid C-cell tumors: Animal studies have found a possible increase in thyroid C-cell tumors, but there is no conclusive evidence in humans yet. However, there is a caveat on the subject.

Wegovy long term side effects

Most of the information on Vigobi has been collected in recent years, so further studies are needed to learn about possible long-term effects. To date, the most common side effects have been gastrointestinal. However, it should be noted that follow-up studies are ongoing.

Discontinuation of Vigobi treatment

Many patients wonder what happens if they stop taking VigRX. The drug is effective as long as it is in sufficient levels in the body. Upon discontinuation of treatment, the familiar feeling of reduced satiety may gradually return, and at the same time, appetite may increase again.

Possible weight gain

If a person returns to a less healthy lifestyle, weight gain is almost certain to occur again. Therefore, it is important to continue to maintain a balanced diet and exercise, even if treatment is discontinued. A doctor should be consulted before making a decision to discontinue or change the dosage.

The importance of medical follow-up

Whether you continue treatment or stop, it is important to have regular medical follow-up. Your doctor can help adjust your treatment based on your body's reactions, side effects, and weight loss progress.

Interactions with other drugs and alcohol

Some people taking Vigo are also taking other medications, especially diabetes medications. There are also many questions about combining it with alcohol.

Wegovy and alcohol

Alcohol itself may increase appetite or impair dietary judgment. Although there is no absolute prohibition, it is recommended to reduce alcohol consumption, especially at the beginning of treatment when nausea is more common. Excessive alcohol consumption may worsen digestive disorders and impair the body's ability to control blood sugar levels.

Combination with other drugs

• Diabetes medications: When combining Vigobi with additional medications (such as insulin or oral medications), blood sugar levels should be monitored to prevent hypoglycemia.
• Other medications: Always inform your doctor about all medications you are taking, including vitamins and supplements. Some medications may affect the metabolism of Semaglutide or vice versa.

Comparison: Vigovac vs Ozempic and Monjaro

Many people know the Ozempic as a cure for diabetes. At the same time, another drug appeared on the market called Mounjaro Based on another substance (Tirzepatide). How does Vigobi compare to them?

Wegovy vs Ozempic

• Treatment goalsOzempic is primarily intended for the management of type 2 diabetes. Vigabatrin has been specifically adapted for the treatment of obesity.
• DosagesOzempic reaches up to 1 mg per week, while Vigoby reaches up to 2.4 mg. The formulations are tailored to the purpose of the treatment.
• Weight loss: Ozempic certainly has a weight loss effect, but VigRX has received official approval as a product for the treatment of obesity.

Wegovy vs Mounjaro

• Active ingredient: Monjero is based on Tirzepatide, which acts on two hormones (GLP-1 and GIP). Vigobi focuses on GLP-1 only.
• Effectiveness for weight loss: Preliminary studies suggest that Monjaro may lead to greater reduction, but this depends on the patient profile. Vigobi is also considered very effective.
• Market approval: Both are approved for use in diabetes. However, Monjero is still in various stages of approval for the obesity indication, while Vigobi is already specifically approved for that purpose.

Wegovy cost and health insurance

The cost of Wegovy varies depending on the country, type of medical insurance, and health insurance fund. In Israel, it may be possible to find partial reimbursements within the framework of supplementary insurance, but it is not always included in the drug basket.

Vigobi Health Fund

Some health funds offer cost-sharing, but this depends on strict criteria of BMI and associated medical conditions. It is recommended to check directly with the health fund and receive updates on the reimbursement policy, as it may change from time to time.

General Vigobi

Within the framework of Clalit Health Services, it must be examined whether the drug is included in the complete or extended insurance agreements. In practice, each fund may establish different internal procedures regarding participation or partial financing.

Vigobi during pregnancy and breastfeeding

Is Vigabatrin suitable for pregnant or breastfeeding women? In general, it is not recommended to use the drug during pregnancy or breastfeeding. Most medical guidelines warn against giving GLP-1 receptor agonists to pregnant women, because we do not know for sure how it affects the fetus.
If you are considering becoming pregnant, it is a good idea to consult a doctor about discontinuing treatment in advance. You should also be informed about breastfeeding plans, as the substance may pass into breast milk.

Is Vigobi dangerous? (Safety and risks)

Like any drug, Vigabatrin requires medical monitoring. The main risks are gastrointestinal side effects, such as nausea and diarrhea. In addition, there is some warning about the possibility of thyroid C-cell tumors, although this has not yet been conclusively proven in humans.
The medication is generally safe when taken as directed by your doctor and your overall health is monitored. It is important to share any unusual problems with your medical team and to have regular checkups.

What is Wegovy?

Wegovy, or by its foreign name, Wegovy, is a semaglutide-based drug intended for the treatment of obesity. It works by mimicking GLP-1, a hormone that helps reduce hunger and increase satiety. The result: substantial assistance with weight loss.

Wegovy mechanism of action

The hormone GLP-1 is secreted after a meal and stimulates a feeling of fullness. Vigobi mimics this activity continuously and higher levels of the hormone reduce appetite, slow gastric emptying and reduce overall calorie intake. Indirectly, this also contributes to improving blood sugar control in patients with type 2 diabetes.

Wegovy for weight loss

The main goal of Vigobi is to achieve significant weight loss in people with a high BMI. This drug affects not only the weight itself, but also the mechanisms of hunger and satiety. When the brain receives stronger signals of satiety, the person can more easily control the amount of food they consume.

Wegovy dosage

The Vigobi dosage scale is divided into five steps: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and finally 2.4 mg (which is considered the full therapeutic dose). The gradual increase usually takes about 16–20 weeks. The process is designed to ensure maximum tolerability for patients and reduce side effects such as nausea.

Is Wegovy suitable for diabetes? (Wegovy for diabetes)

Vigoby can also help people with type 2 diabetes, especially since semaglutide is known as a drug that improves insulin sensitivity and balances blood sugar levels. However, the official indication for semaglutide under the name Vigoby is the treatment of obesity. Drugs like Ozempic are the original indication for diabetes. It is important to consult a doctor to choose the right drug.

How much does Wegovy cost?

The cost of Vigobi is affected by parameters such as health insurance policies, availability in the health fund, and importation of the drug. In some cases, the patient may pay a reduced deductible if they meet the criteria of a supplementary health plan or private insurance. It is recommended to check with the health fund or insurance company for an up-to-date price estimate.

How to get Wegovy?

To get a prescription for Vigobi, you should contact your family doctor or a specialist (e.g. an endocrinologist). The doctor will examine your BMI, medical history, and suitability for treatment. The medication can then be purchased at licensed pharmacies. You should check whether your insurance policy covers part of the cost.

Wegovy medication

Vigobi is considered a breakthrough drug in the field of weight loss. This is due to its high efficacy in clinical studies and its focus on a large group of patients who require assistance beyond a normal lifestyle change. However, as with any drug, it requires close medical guidance and a personalized suitability test.

The obesity epidemic

Vigobi is primarily intended for the treatment of obesity. Various health organizations around the world recognize it as an important medicine for patients with a BMI ≥ 30 or BMI ≥ 27 with another risk factor. Its goal is to enable these individuals to find an intervention framework that will help them achieve significant weight loss.

Frequently Asked Questions (FAQ)

Question: Will Vigobi be suitable for everyone who is overweight?

answerA: Not necessarily. Vigobi is intended for those with a BMI of 30 or higher (obesity), or 27 or higher with concomitant medical conditions. Even then, the doctor examines additional factors and decides on the appropriateness of the treatment.

Question: Can Vigabatrin be combined with other diabetes medications?

answerA: Yes, but close monitoring is required. Combination with insulin or oral diabetes medications requires frequent blood sugar testing to prevent hypoglycemia.

Question: What happens if treatment is stopped?

answer: Usually, the increased feeling of fullness decreases and appetite may increase again. If you return to old habits, there is a risk of weight gain.

Question: Is Vigova safe during pregnancy?

answer: It is not recommended to use Vigovi during pregnancy or breastfeeding. Most medical organizations warn that there is not enough data on its effect on the fetus and the nursing mother.

Question: How can side effects such as nausea be reduced?

answer: Starting treatment at a low dose and gradually increasing it helps the body adapt. It is advisable to eat small, frequent meals, drink enough water, and choose foods that are easy to digest.

Question: Does Vigobi eliminate the need for physical activity?

answerA: No. Weight loss medications are much more effective when combined with a balanced diet and regular exercise. This combination is important for an overall improvement in quality of life.

Question: Can I purchase Vigobi without a prescription?

answerA: No. Vigovaya is a prescription drug. A doctor must approve the treatment, as it requires a compatibility test and monitoring for side effects.

Question: Are there any gastric bypass surgeries that are better than Vigobes?

answerBariatric surgery is considered an option for people with severe obesity. However, many prefer to first try a drug treatment such as Vigabatrin before moving on to invasive surgery.

Question: How long is it recommended to stay on Vigobi?

answer: There is no absolute restriction. Some patients continue for months to years, depending on weight goals and health status. The doctor should be consulted regularly.

Recommended external links

1. The Israeli Diabetes Association – General information about the treatment of diabetes, obesity and related medications.
2. The US FDA – Official information on approved drugs, including Wegovy and Ozempic, and current guidelines in the therapeutic field.

(These links provide supplementary and reliable information, but should not be considered a substitute for personal professional advice.)

Summary

Wigwam (Wegovy) Considered one of the most promising drugs for the treatment of obesity, thanks to its ability to mimic the hormone GLP-1 and increase satiety over time. It is intended for adults with a BMI ≥ 30, or a BMI ≥ 27 with at least one medical risk factor. To increase its effectiveness, a balanced diet and physical activity should be incorporated into the daily routine.
The drug works in a gradual, increasing dose, until the therapeutic dose of 2.4 mg is reached. During treatment, patients may experience nausea, vomiting, or indigestion, but most of them adapt later. Serious side effects are relatively rare, but require medical monitoring.
After stopping treatment, weight gain may occur again if you do not maintain a healthy lifestyle. It is also important to follow your doctor's instructions regarding combining Vigobi with other medications or alcohol.
Comparing Vigabatrin to Ozempic or Monjero reveals similarities in terms of mechanism of action, but the main difference is in the indications and maximum dosage. Vigabatrin is more focused on the treatment of obesity, while Ozempic is primarily intended for diabetes. Monjero is another option with a dual mechanism.
Along with the potentially high cost, people eligible for reimbursement through supplementary insurance may benefit from participation. In any case, it is recommended to consult directly with the health fund or insurance company regarding the latest policy.
Ultimately, Vigobi is a significant tool for those who have difficulty losing weight through diet and exercise alone. With proper medical monitoring and a combination of healthy lifestyle habits, you can expect consistent and powerful weight loss.